Med J Bakirkoy. 2021; 17(1): 48-52 | DOI: 10.5222/BMJ.2021.43534

Can Our Blood Groups Determine Our Life Expectancy?

Gulcin Sahingoz Erdal¹, Ismail Býyýk², Pinar Kasapoglu³, muhammet hulusi satýlmýþoðlu⁴, Nilgun Isiksacan^3
1Health Science University,bakirkoy Dr Sadi Konuk Training And Research Hospital, Department Of Internal Medicine, Istanbul, Turkey
²Usak University, School Of Medicine, Education And Research Hospital,department Of Cardiology, Usak, Turkey
³Health Science University, Bakirkoy Dr Sadi Konuk Training And Research Hospital, Department Of Biochemistry,istanbul, Turkey
⁴Health Science University, Mehmet Akif Ersoy Training And Research Hospital, Department Of Cardiology, Istanbul, Turkey

Background/aim: In this study, we aimed to investigate the relationship between long-term mortality and survival with ABO blood group in patients with acute coronary syndrome.
Materials and methods: This observational study was carried out in two tertiary hospitals. 192 patients followed for 72 months due to acute coronary syndrome, showing a balanced distribution for ejection fraction, additional diseases and age, were included in the study.
Results: The survival rate was evaluated in 72 months follow-up. In the survival analysis according to individual blood groups; there was no statistically significant difference between the groups. When the patients were divided into two groups, there was 24.39% mortality in those with O blood group and 15.23% mortality in those without O blood group (p>0.05). Although it was not statistically significant, in patients with O blood group, an increasing tendency was observed in 72 month mortality (p>0.05). There was no association between Rh antigen and survival in this study (p=0.79).
Conclusion: Although it was not able to reach statistically significance limit, a decreasing tendency in long-term survival was observed in patients with O blood group compared to those without O blood group in patients with acute coronary syndrome. The results should be confirmed by larger prospective studies.

Keywords: acute coronary syndrome, ABO blood groups, mortality, survival

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Kan Gruplarýmýz Hayat Uzunluðumuzu Belirleyebilir mi?

Gulcin Sahingoz Erdal¹, Ismail Býyýk², Pinar Kasapoglu³, muhammet hulusi satýlmýþoðlu⁴, Nilgun Isiksacan^3
1Saðlýk Bilimleri Üniversitesi, Bakýrköy Dr. Sadi Konuk Eðitim Ve Araþtýrma Hastanesi,i̇ç Hastalýklarý Ana Bilim Dalý, Istanbul, Türkiye
²Uþak Üniversitesi Týp Fakültesi Eðitim Ve Araþtýma Hastanesi, Kardiyoloji Ana Bilim Dalý, Uþak, Türkiye
³Saðlýk Bilimleri Üniversitesi, Bakýrköy Dr. Sadi Konuk Eðitim Ve Araþtýrma Hastanesi, Biyokimya Ana Bilim Dalý, Istanbul, Türkiye
⁴Saðlýk Bilimleri Üniversitesi, Mehmet Akif Ersoy Eðitim Ve Araþtýrma Hastanesi, Kardiyoloji Ana Bilim Dalý, Istanbul, Türkiye

Amaç: Bu çalýþmada akut koroner sendromlu hastalarda ABO kan grubu ile saðkalým ve uzun-süreli mortalite arasýndaki iliþkiyi araþtýrmayý amaçladýk.
Gereç ve yöntem: Bu gözlemsel çalýþma, iki adet üçüncü basamak hastanede gerçekleþtirildi. Ejeksiyon fraksiyonu, ek hastalýklar ve yaþ için dengeli bir daðýlým gösteren akut koroner sendrom nedeniyle 72 ay takip edilen 192 hasta çalýþmaya dahil edildi.
Bulgular: Saðkalým oraný 72 aylýk takipte deðerlendirildi. Bireysel kan gruplarýna göre saðkalým analizinde; gruplar arasýnda istatistiksel olarak anlamlý fark yoktu. Hastalar iki gruba ayrýldýðýnda, O kan grubu olanlarda % 24.39, O kan grubu olmayanlarda % 15.23 mortalite vardý (p> 0.05). Ýstatistiksel olarak anlamlý olmasa da, O kan grubundaki hastalarda 72 aylýk mortalitede artýþ eðilimi gözlendi (p> 0.05). Bu çalýþmada Rh antijeni ile saðkalým arasýnda bir iliþki yoktu (p = 0.79).
Sonuç: Ýstatistiksel olarak anlamlýlýk sýnýrýna ulaþamamasýna raðmen, akut koroner sendromlu hastalarda O kan grubu olmayanlara göre O kan grubundaki hastalarda uzun dönem saðkalýmda azalma eðilimi gözlenmiþtir. Sonuçlar daha büyük prospektif çalýþmalarla doðrulanmalýdýr.

Anahtar Kelimeler: akut koroner sendrom, ABO kan gruplarý, mortalite, saðkalým

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