ISSN: 1305-9327

 
 

VOLUME: 14 NUMBER: 1
 
 

Login | Register | Forgot Your Password?|



Online article submission system has been turned over to ScopeMed. We kindly request you to submit your current article or new articles via ScopeMed system
COPYRIGHT TRANSFERM FORM
AUTHOR FORM
ICMJE FORM
INFORMATION for AUTHORS
Print version of Medical Journal of Bakirkoy has been stopped as of 2018; the journal continues to be published as e-journal starting with March 2018 issue.

RSS Feed
 
 
11 - Our experiences of intravenous thrombolytic treatment in acute ischemic stroke
   
Murat Çabalar, Nilay Taşdemir, Hacı Ali Erdoğan, Vildan Yayla, Nejla Sözer, Sultan Çağırıcı, Hülya Ertaşoğlu Toydemi
   
  ABSTRACT
   
  Objective: Our aim was to evaluate the data of the patients who had acute ischemic stroke and to whom we had administered iv r-tPA in our stroke unit.

Materials and Methods: We included 92 patients who had received iv r-tPA after acute ischemic stroke between 2012 and 2016. Demographic and clinical features of the patients, NIHSS and mRS values at the begining and at the end of hospitalization period and at 1st and 3rd month-follow-up, symptom-to-door, door-to-needle, symptom-to-needle times, ASPECT scores and the existance of complications were recorded. A value of p≤0.05 was considered significant.

Results: Ninety-two patients (42 females and 50 males), ranging in age from 33 to 88 years (mean age±SD: 64.98±11.92 years), were evaluated. Mean ASPECT score was 9.62±0.76. The difference regarding the decrease in NIHSS scores recorded at the symptom onset and at the end of hospitalization was significant (p<0.01). There was no significant relationship between NIHSS and mRS scores at the end of hospitalization period and symptom-to-door, door-to-needle, symptom-to-needle times (p>0.05). Intracranial hemorrhage was observed in 22 patients (23.9%) and exitus was recorded in 20 patients (21.7%).

Conclusion: Intravenous r-tPA administration to patients who were admitted to hospital in the first 3 hours after stroke onset has been proven to be beneficial. Multidisiplinary approach with experienced staff may lead to an increase in the success of this treatment.
   
  Keywords
  Ischemic stroke, tissue plasminogen activator, intravenous
   
  To download fulltext click here